一、中文名称：AntiPEGAntibody，PEG抗体

二、产品描述

聚乙二醇（PEG）是由重复的乙二醇单元构成的高分子化合物，具有优良的亲水性、生物兼容性及无毒性，且不具抗原性。PEG化修饰能够显著改变药物的物理化学性质，延长其在血浆中的半衰期与吸收时间，同时影响药物与细胞受体的结合亲和力，从而提升肿瘤靶向性。在PEG化修饰药物的研究中，抗PEG抗体是不可或缺的重要工具，能够用于监测药物的药代动力学特性，包括其分布、代谢和排泄过程。此外，抗PEG抗体也在聚乙二醇化蛋白质或分子（例如纳米颗粒）的质量控制中扮演重要角色。尊龙凯时的Antibodysystem PEG系列抗体非常适合用于ELISA、WB和HC等多种实验应用。

三、相关产品

• Anti-PEGAntibody(E112#)(RGK24701)
• Anti-PEGAntibody(6A9/PEG2)(RGK24702)
• Anti-PEGAntibody(14B5/PEG1a)(RGK24703)
• Anti-PEGAntibody(14B5/PEG1b)(RGK24704)
• Anti-PEGAntibody(331)(RGK24705)
• Anti-PEGAntibody(2B5)(RGK24706)
• Anti-PEGAntibody(32D6)(RGK24707)
• Anti-PEGAntibody(AGP3)(RGK24708)
• Anti-PEGAntibody(63)(RGK24709)
• Anti-PEGAntibody(15-2b)(RGK24710)

四、产品详情

名称：Anti-PEGAntibody(E112#)(RGK24701)
别名：PEG、Poly(ethyleneglycol)、Polyethyleneglycol
货号：RGK24701
宿主：Mouse
同种型：IgG1, kappa
克隆类型：Monoclonal
靶标：PEG、Poly(ethyleneglycol)、Polyethyleneglycol
浓度：1mg/ml
内毒素水平：请咨询实验室获取信息
纯度：经SDS-PAGE测定为95%
纯化方式：由细胞培养上清液中经过Protein A/G纯化
克隆号：E112#
应用：ELISA、WB
状态：液态
保存溶液：0.01M PBS，pH 7.4
稳定性和存储：使用手动解冻的冰箱，避免反复冻融循环，短期存储于4°C（1-2周），长期存储于-20°C（12个月），或-80°C（长期）。

五、参考文献

• Anti-PEG antibodies in the clinic: Current issues and beyond PEGylation PMID: 27369864
• “PEG dilemma” for liposomes and its solving approaches PMID: 26118102
• Chemistry Routes for Copolymer Synthesis Containing PEG for Targeting, Imaging, and Drug Delivery Purposes PMID: 31336703
• Anti-PEG IgM production induced by PEGylated liposomes as a function of administration route PMID: 37355210
• Exosome isolation based on polyethyleneglycol (PEG): a review PMID: 39702782
• Quantitation of PEG on PEGylated Gold Nanoparticles Using Reversed Phase High Performance Liquid Chromatography and Charged Aerosol Detection: Version 10 PMID: 39012983
• PEG-lipid micelles as drug carriers: physiochemical attributes, formulation principles and biological implication PMID: 25547369
• Safety Evaluation of Polyethylene Glycol (PEG) Compounds for Cosmetic Use PMID: 26191379
• Free PEG Suppresses Anaphylaxis to PEGylated Nanomedicine in Swine PMID: 38469811
• Stepwise PEG synthesis featuring deprotection and coupling in one pot PMID: 35079293
• The Importance of Poly(ethyleneglycol) Alternatives for Overcoming PEG Immunogenicity in Drug Delivery and Bioconjugation PMID: 32024289
• Missing PEG tube found at the ileocecal valve PMID: 34401032
• Polyethylene Glycol PMID: 30694626
• Investigation of anti-PEG antibody response to PEG-containing cosmetic products in mice PMID: 36632951
• The uses and properties of PEG-linked proteins PMID: 1458545
• Accelerated clearance by antibodies against methoxy PEG depends on pegylation architecture PMID: 36641121

如需详细信息，请咨询尊龙凯时的中国授权总代理——武汉佰乐博生物技术有限公司。作为法国Antibodysystem品牌在亚洲区的授权总代理，我们提供近三万种蛋白、抗体等核心生命科学试剂，致力于为生命科学研究者提供专业、全面、可靠的试剂产品。

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